Comprehesive analysis on the histological classifications in 42 197 cases of ovarian tumors in China

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Objective:The histological types of ovarian tumors were investigated and analyzed in China in order to compare with those in other countries,which will benefit to the prevention and treatment of ovarian cancer.Methods:The pathological data from 42 197 cases of ovarian tumors in ten years during 1980 to 1989 were registered according to the WHO classification for ovarian tumors. Some indefinite cases pathologically in the first diagnosis should bereconfirmed according to the WHO classification.Results: Forty-two thousand one hundred and ninety seven cases ofovarian tumors were selected from all tumors in 21 provinces and 3 major regional cities in China.There were 10 288(24.4%) malignant tumors in all cases.They were composed by 5 650(54.9%) cases of epithelial tumors,1 871(18.2%) cases of germ cell tumors,837(8.5%) cases of sex cord tumors,1 003(9.7%) cases of secondarytumors,and 891(8.7%) cases of other tumors.The malignant tumors constituent ratios were 58.5% and 50.9% respectively in the north and south of the Yangtze River..The histological types of ovarian tumors were about the same ratios,but the malignant tumors were different in Chinese six major administrative region andalso in the region both north and south of the Yangtzy River.The ratio of borderline epithelial ovarian tumors to epithelial tumors was 1:5.9.Borderlineserous cystadenocarcnoma appeared to be similar to borderline mucinous cystadenocarcinoma in frequency.Serous cystadenocarcinoma was found to be the most frequent one in malignant epithelial tumors.Conclusion:Compared with reports abroad,the different types of malignant ovarian tumors inChina represent a different distributive pattern.The malignant epithelial ovarian tumors were lower than that in other countries (55% vs 80%-90%),while the malignant germ cell tumors and sex cord stromal tumors were 6 and 3 times higher thanthose abroad,the main metastasizing tumors come from gastroenteric carcinoma,while the metastasizing tumors from breast cancer were only 2.5%.
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