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目的:评价补充锌剂治疗在小儿病毒性肠炎的疗效和发病后2月内腹泻发生率的影响。方法:随机把我院2012年2个月~1013年12月诊断符合轮状病毒(RV)肠炎标准的患儿共83例,随机分为治疗组42例,对照组41例(男47例,女36例),治疗组和对照组均给予口服补液或静脉补液,口服肠粘膜保护剂、肠道微生态制剂等对症治疗,治疗组加用葡萄糖酸锌补充元素锌。结果:治疗组病程6.25±1.31天;对照组病程7.66±1.52天。2组差异有统计学意义(P<0.05)。治疗组病程缩短,临床症状缓解较快,随访有效预防腹泻再发作用,治疗组再发率(4/42)9.52%,对照组再发率(13/14)31.7%,2组差异有统计学意义(P<0.05)。结论:增补锌剂治疗RV肠炎能显著改善临床症状,缩短病程,且无不良反应,提高治疗有效率,预防腹泻发生。
PURPOSE: To evaluate the efficacy of zinc supplementation in pediatric viral enteritis and the incidence of diarrhea within two months of onset. Methods: A total of 83 children diagnosed with rotavirus (RV) enteritis in our hospital from January 2012 to December 2013 were randomly divided into treatment group (n = 42) and control group (n = 47) Female 36 cases), the treatment group and the control group were given oral rehydration or intravenous rehydration, oral gut mucosal protective agent, intestinal probiotics and other symptomatic treatment, the treatment group with zinc gluconate supplementation of zinc. Results: The course of treatment was 6.25 ± 1.31 days in control group and 7.66 ± 1.52 days in control group. The difference between the two groups was statistically significant (P <0.05). The course of treatment was shortened, the clinical symptoms were relieved quickly, and follow-up was effective in preventing the recurrence of diarrhea. The recurrence rate was 9.52% in the treatment group (31/14) and 31.7% in the control group Significance (P <0.05). Conclusion: Zinc supplementation for the treatment of RV enteritis can significantly improve the clinical symptoms, shorten the course of the disease, and no adverse reactions, improve the treatment efficiency, prevent diarrhea.