复方制剂是否要发展,前一个时期我国有许多不同看法;近年随着几类新的复方制剂的出现和被医疗单位、患者所接受,已不辩自明。对国内外复方制剂发展全貌进行综述很困难,下面仅对主要的几类新复方制剂做一介绍,反映的是复方制剂的发展趋势。一、青霉素类由于长期应用青霉素类药物,细菌分泌的β—内酰胺酶大大降低了青霉素类药物的治疗价值,所以国外十分注重发展β—内酰胺酶抑制剂和青霉素类药物与β—内酰胺酶抑制剂的复方制剂。已经证明有较大意义的β—内酰胺酶抑制剂主要有棒酸(克拉维 Whether the development of compound preparations, the previous period of our country has many different views; in recent years with the emergence of several new types of compound preparations and by medical units, patients accepted, no self-evident. It is very difficult to review the whole picture of the development of compound preparations both at home and abroad. The following is a brief introduction of the main types of new compound preparations, which reflect the development trend of compound preparations. First, penicillins due to long-term use of penicillins, bacterial secretion of β-lactamase greatly reduced the therapeutic value of penicillin drugs, so very much attention to the development of foreign β-lactamase inhibitors and penicillins and β-lactam Enzyme inhibitor compound preparation. It has been shown that the more potent β-lactamase inhibitors are clavulanic acid (clavulanate)