论文部分内容阅读
目的:揭示儿童使用抗精神病药的不良反应概况以及不良反应的发生规律.对象与方法:采用医院集中监测的方法,对81例住院儿童进行了为期12个月的抗精神病药不良反应流行病学研究.结果:监测期共有55名患儿发生了185例次不良反应症状,其发生率为67.9%;A型、B型不良反应分别占178和7例次,轻、重度不良反应症状分别占123和62例次;用药种类、性别以及疾病种类与不良反应的发生有显著性相关.结论:应重视儿童抗精神病药不良反应的监测工作;在治疗上,儿童不宜长期服用抗精神病药.
OBJECTIVE: To reveal the general situation of adverse reactions of children using antipsychotic drugs and the occurrence of adverse reactions.Materials and Methods: 81 hospitalized children were enrolled in this study. The 12-month epidemiology of antipsychotics Results: A total of 185 children in the monitoring period had 185 adverse reactions, the incidence rate was 67.9%; type A and type B adverse reactions accounted for 178 and 7 cases respectively, mild and severe adverse reactions accounted for 123 and 62 cases.The types of medication, sex and disease types were significantly correlated with the incidence of adverse reactions.Conclusion: Children should pay attention to the monitoring of adverse reactions of antipsychotics.It is not advisable for children to take long-term antipsychotics in treatment.