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测定150名绝经后妇女骨密度（BMD）和血清雌二醇（E2）、甲状旁腺素（PTH）、睾酮（T）及血清25—羟维生素D3[25（OH）D3]。结果显示，绝经后妇女BMD、血清E2和25（OH）D3水平显著低于中青年妇女对照组，PTH水平显著高于中青年妇女对照组，血清T水平两组间差异不显著。BMD与上述激素间存在显著相关关系。提示绝经后妇女BMD下降与体内有关的内分泌激素的失调密切相关，体内与骨代谢有关的内分泌激素的失调可能是导致地经后妇女骨质疏松症的重要病因。
BMD, E2, PTH, T and serum 25-hydroxyvitamin D3 [25 (OH) D3] in 150 postmenopausal women were measured. The results showed that the levels of BMD, serum E2 and 25 (OH) D3 in postmenopausal women were significantly lower than those in young and middle-aged women, and the PTH levels were significantly higher in the postmenopausal women than in the young and middle-aged women. There was no significant difference in serum T levels between the two groups. There is a significant correlation between BMD and the above hormones. It is suggested that the decline of BMD in postmenopausal women is closely related to the imbalance of endocrine hormones in the body. The imbalance of endocrine hormones related to bone metabolism in vivo may be the important etiology of postmenopausal women with osteoporosis.