论文部分内容阅读
目的 探讨原发痛风对血脂、凝血和纤溶活性的影响。方法 1996年 1月～ 2 0 0 0年 12月原发痛风患者 133人 ,与健康者 (正常对照 ) 135人做病例对照研究 ,比较血脂、凝血和纤溶活性指标的变化 ,血脂引入条件Logistic回归分析。结果 病例与对照两组均数比较 ,TG、LDL、VLDL、apo -B、Lp(a)病例组明显高于对照 (P <0 .0 1) ;HDL -C、HDL 2 -C病例组低于对照组。病例与对照两组均数比较 ,结果显示 :TG、LDL、VLDL、apo -B、Lp(a)病例组明显高于对照 (P <0 .0 1) ;HDL -C、LDL 2 -C病例组低于对照组 ,TG、TC、LDL、VLDL的升高及HDL 3-C的降低与痛风危险存在统计学相关。tPA明显低于对照 ;PAI病例组明显高于对照组。结论 原发痛风患者早期需防治动脉粥样硬化
Objective To investigate the effects of primary gout on blood lipid, coagulation and fibrinolytic activity. Methods From January 1996 to December 2000, 133 patients with primary gout and 135 healthy subjects (normal control) were enrolled in this study. The changes of blood lipids, coagulation and fibrinolytic activity were compared. Logistic regression regression analysis. Results Compared with the control group, the cases of TG, LDL, VLDL, apo-B and Lp (a) were significantly higher than those of the control (P <0.01); HDL-C and HDL 2-C In the control group. The results showed that the cases of TG, LDL, VLDL, apo-B and Lp (a) were significantly higher than those of the control (P <0.01), HDL-C and LDL 2-C Group lower than the control group, TG, TC, LDL, VLDL and HDL 3-C decreased with the risk of gout exist statistically significant. tPA was significantly lower than the control; PAI cases were significantly higher than the control group. Conclusion Primary gout patients need prevention and treatment of atherosclerosis early