作者以前的研究就曾发现松果体的吲哚类激素—褪黑激素(melatonin)抑制新生大鼠的垂体对LHRH所引起的LH和FSH的分泌。但未能揭示褪黑激素抑制垂体机能是带普遍性还是选择性地作用到促性腺激素的细胞。本研究的目的是为了确定褪黑激素抑制垂体的选择性作用。 实验用初生6—7天的Spragne-Dawley大鼠。雌雄仔鼠混用或只用雌性。动物从出生后则控制在一定的光照环境中(光—14小时,暗—10小 The authors previously found that the pineal hormone indole hormone, melatonin, inhibits LHRH-induced LH and FSH secretion in the pituitary of neonatal rats. But failed to reveal whether melatonin suppresses the pituitary function to be prevalent or to gonadotrophin-producing cells. The purpose of this study was to determine whether melatonin inhibits pituitary selectivity. Spragne-Dawley rats, 6-7 days old, were used experimentally. Male or female pups mix or only female. Animals from birth control in a certain light environment (light -14 hours, dark -10 hours