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本文报告了多抗甲素增强胸腺免疫机能的超微结构依据。给小鼠腹腔注射多抗甲素100mg/kg,连续3～5日,用电镜观察发现,小鼠胸腺皮质和髓质的淋巴细胞体积增大、胞核增大、核形态不规则,胞浆增多,细胞器由较少变得丰富,以线粒体和核蛋白体增加明显,并且出现过渡型转化淋巴细胞。电镜研究表明,淋巴细胞的核酸、蛋白质及多糖类物质的合成代谢活跃。说明多抗甲素对胸腺可以产生直接影响,通过这种影响增强了胸腺的免疫机能。
This article reports the ultrastructural basis of poly-A for enhancing thymus immune function. The mice were injected intraperitoneally with 100 mg / kg of poly-A for 3 to 5 days. Electron microscopy showed that the lymphocytes in the cortex and medulla of mouse thymus increased in size, with enlarged nuclei, irregular nuclei and cytoplasm Increased, organelles from less to rich in mitochondria and nucleoprotein increased significantly, and the emergence of transitional type transitional lymphocytes. Electron microscopy studies have shown that the synthesis and metabolism of lymphocyte nucleic acids, proteins and polysaccharides are active. Polystatin A shows that the thymus can have a direct impact, through this effect to enhance the immune function of the thymus.