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目的:研究菊科药用植物三角叶凤毛菊Saussurea deltoidea的化学成分。方法:利用正/反相硅胶柱层析色谱、凝胶分子筛色谱、HPLC等色谱方法进行化合物的分离,利用波谱学方法鉴定化合物结构。结果:从三角叶凤毛菊中分离出10个化合物,其结构分别鉴定为(3R,6R,7E)-3-hydroxy-4,7-megastigmadien-9-one(1),(3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-me-gastigmen-9-one(2),3-hydroxy-β-damascone(3),S-(+)-dehydrovomifoliol(4),megastigman-5-ene-3β,9R-diol(5),coniferaldehyde(6),β-hydroxypropiovanillone(7),3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone(8),dihydrosyringenin(9),4-[(1S)-3-hydroxy-1-methoxypropyl]-2,6-dimenthoxyphenol(10)。结论:化合物1～10均是首次从该植物中分离得到。
Objective: To study the chemical constituents of Saussurea deltoidea, a medicinal plant of Asteraceae. Methods: The compounds were separated by silica gel column chromatography, gel chromatography and HPLC. The structures of the compounds were identified by spectroscopic methods. Results: Ten compounds were isolated from Saururus chinensis, whose structures were identified as (3R, 6R, 7E) -3-hydroxy-4,7-megastigmadien-9- 7E) -5,6-epoxy-3-hydroxy-7-me-gastigmen-9- one (2), 3-hydroxy-β-damascone (3) 5-ene-3β, 9R-diol (5), coniferaldehyde (6), β-hydroxypropiovanillone (7), 3-hydroxy- Dihydrosyringenin (9), 4 - [(1S) -3-hydroxy-1-methoxypropyl] -2,6-dimenthoxyphenol (10). Conclusion: Compounds 1 ~ 10 were isolated from this plant for the first time.