由于乙胺碘呋酮干扰甲状腺的代谢,造成血清T_4~-和反T_3~(?)(rT_3~(?))的升高及T_3~(?)水平的微降。目前己有报告阐述了rT_3~(?)与乙胺碘呋酮的疗效和毒性的相关性,而本文研究却进一步澄清了这一关系。方法:31例病人中男21例,女10例,平均年龄62±11岁,患有频发和复杂性早搏(VPCS)且对常规抗心律失常药物无效,停用药物至少5个半衰期后作为乙胺碘呋酮治疗前基础研究,测定血清 As amiodarone interfered with thyroid metabolism, the increase of T_4 ~ - and anti-T_3 ~ (?) (RT_3 ~ (?)) And the decrease of T_3 ~ (? At present, it has been reported on the rT_3 ~ (?) And amiodarone efficacy and toxicity of the correlation, but the study further clarify this relationship. Methods: There were 21 males and 10 females in 31 patients with a mean age of 62 ± 11 years. They had frequent and complicated premature beats (VPCS) and had no effect on conventional antiarrhythmic drugs. After discontinuing the drug for at least 5 half-lives, Ethnofenadine treatment before the basic research, determination of serum