软骨对硫有高度的摄取能力,已有许多研究反复证明。Dziewiatkowski等应用放射性同位素(S~35)系统地研究了这一课题,证明软骨细胞摄取放射性硫,用以合成硫酸软骨素,并将后者沉积于细胞外,成为细胞间基质的主要组成部分。Bostrom等用类似的方法证明硫酸软骨素中的硫酸根处于经常的代谢更新状态,其生物半衰期(大鼠)为16天。可见,放射性同位素的应用,为研究软骨代谢提供了许多事实材料和便利条件。关于软骨代谢的调节问题,研究多集中干内分泌方面。已经阐明,软骨摄取放射性硫的能力,受脑下垂体和甲状腺的影响。此 Cartilage has a high ability to uptake sulfur, many studies have repeatedly proved. Dziewiatkowski and other radioisotopes (S ~ 35) systematically studied this issue, proof of chondrocytes uptake of radioactive sulfur for the synthesis of chondroitin sulfate, and the latter deposited in the extracellular matrix as a major component of the cell. In a similar way, Bostrom et al. Demonstrated that sulphate in chondroitin sulfate is frequently metabolically renewed with a biological half-life (in rats) of 16 days. Can be seen that the application of radioisotope, cartilage metabolism to provide a lot of factual material and convenience conditions. On the regulation of cartilage metabolism, research and more focus on dry endocrine aspects. It has been clarified that the ability of cartilage to absorb radioactive sulfur is influenced by the pituitary gland and the thyroid. this