Wilson 氏病为一种遗传性的铜代谢疾病,其血清中的铜转运蛋白和血浆铜蓝蛋白都减少,并因铜沉积于肝脏和神经系统而致进行性功能障碍。迟发性皮肤卟啉症(PCT)为一种获得性肝性卧啉症,具有家族发病的倾向。两者都是罕见的疾病。作者报告一例 Wilson 氏病在进行铜螯合疗法的过程中并 Wilson’s disease is an inherited disorder of copper metabolism with reduced levels of both copper transporters and ceruloplasmin in the serum and progressive dysfunction due to the deposition of copper on the liver and the nervous system. Late-onset cutaneous porphyria (PCT) is an acquired hepatic rhinopathy with a familial propensity to develop. Both are rare diseases. The authors report a case of Wilson’s disease during copper chelation therapy