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目的 了解狼疮肾炎 (LN)继发真菌感染情况及其危险因素。方法 通过 93例LN继发感染现状调查 ,发现 4 5例即 4 8 4 %发生了不同程度的多种医院感染 ,其中真菌感染为 2 2 6 % ,2例直接死于真菌感染。感染的病源谱除有真菌外 ,同时还有病毒、细菌 ,但以真菌和细菌为主 ,侵犯部位主要为泌尿道、胃肠道和呼吸道。结果 致感染因素与使用激素、免疫抑制剂、抗生素、介入性操作、肾功能不全、住院时间长等密切相关。结论 加强狼疮性肾炎继发感染的防治是提高LN存活率的重要突破口。
Objective To understand the secondary fungal infection in lupus nephritis (LN) and its risk factors. Methods According to the survey of 93 cases of secondary LN infection, 45 cases (448%) had various kinds of nosocomial infections in varying degrees, of which 22.6% were fungal infections and 2 died of fungal infections directly. In addition to the source of the spectrum of infection with fungi, but also viruses, bacteria, but mainly to fungi and bacteria, the main violations of the urinary tract, gastrointestinal tract and respiratory tract. The results of infection factors and the use of hormones, immunosuppressive agents, antibiotics, interventional procedures, renal insufficiency, length of hospital stay is closely related. Conclusion To strengthen the prevention and treatment of secondary infection of lupus nephritis is an important breakthrough to improve the survival rate of LN.