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腺病毒载体研究的发展使基因治疗付诸于临床应用成为可能，它以遗传毒性低、致病性小、宿主范围广、滴度高、装载容量大等优势已广泛用于基因治疗。腺病毒载体能感染增生分裂细胞及非增生分裂细胞，相同的腺病毒载体对不同的靶细胞可能会产生不同的作用，阐明腺病毒载体转染效
The development of adenoviral vector research makes it possible to put gene therapy into clinical application. It has been widely used in gene therapy because of its low genotoxicity, small pathogenicity, wide host range, high titer and large loading capacity. Adenovirus vectors can infect proliferating and dividing cells and non-proliferating cells, and the same adenovirus vector may have different effects on different target cells. The effect of adenovirus vector transfection