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采用一次性被动回避条件反应——跳台法及避暗法行为实验和3种化学药物所致记忆障碍的模型,观察了健脑灵对小鼠学习记忆的影响。结果表明,健脑灵(800mg/kg)可改善东茛菪碱引起的记忆获得障碍;并对蛋白质合成抑制剂(氯霉素)造成的记忆巩固不良以及30％乙醇引起的记忆再现障碍均有拮抗作用。
A one-time passive avoidance condition-response-jumping method, avoidance behavior test, and three chemical-induced memory impairment models were used to observe the effects of Jiannaoling on learning and memory in mice. The results showed that Jiannaolin (800mg/kg) can improve memory acquisition disorders caused by scopolamine; and there are memory consolidation problems caused by protein synthesis inhibitors (chloramphenicol) and memory regeneration caused by 30% ethanol. Antagonism.