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克林霉素自1970年上市以来已20多年.其抗菌活性强,抗菌谱广,对许多革兰阳性需氧菌、厌氧菌具有抗菌活性.对衣原体、支原体、恶性疟原虫和弓形虫也有活斗志性.在用于治疗多种感染包括危及生命的重症感染患者中,取得了良好疗效.我国目前除口服用克林霉素外,分装和自行合成的注射用克林霉素也即将上市.本文就克林霉素的临床应用(着重在内科感染性疾病和传染病方面)及其相关问题作一扼要介绍.
Clindamycin has been in the market for more than 20 years since it was introduced in 1970. Its antibacterial activity is strong and its antibacterial spectrum is broad, which has antibacterial activity against many gram-positive aerobic and anaerobic bacteria, and also against Chlamydia, Mycoplasma, Plasmodium falciparum and Toxoplasma gondii Active in fighting for a variety of infections, including life-threatening infections in patients with good results have been achieved. In addition to oral administration of clindamycin in our country, the dispensing and self-synthesis of clindamycin for injection will soon This article gives a brief introduction of the clinical application of clindamycin (focusing on medical infectious diseases and infectious diseases) and related issues.