论文部分内容阅读
生物医用可降解镁合金具有良好的机械性能、生物可降解性且降解产物可随人体新陈代谢排出体外,被誉为“下一代生物医用金属材料”。然而,过快的降解速率制约着镁合金在临床上的应用。从生物降解性和生物相容性的角度,综述医用可降解镁合金表面改性研究进展。重点介绍医用可降解镁合金表面微弧氧化涂层、Ca–P基涂层和惰性陶瓷涂层等生物陶瓷涂层的制备及其优缺点。最后,基于医用镁合金的临床应用要求和现有表面改性技术特点,展望医用可降解镁合金表面改性的未来发展方向。
Biomedical biodegradable magnesium alloy has good mechanical properties, biodegradability and degradation products can be excreted with the body’s metabolism, known as “the next generation of biomedical metal materials.” However, excessive degradation rate restricts the clinical application of magnesium alloys. From the perspective of biodegradability and biocompatibility, the research progress of surface modification of medical degradable magnesium alloy is reviewed. The preparation of bioceramic coatings such as micro-arc oxidation coatings on medical degradable magnesium alloys, Ca-P-based coatings and inert ceramic coatings, and their advantages and disadvantages are introduced. Finally, the future development of medical biodegradable magnesium alloy surface modification is prospected based on the clinical application requirements of medical magnesium alloy and the existing technical characteristics of surface modification.