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成人急性乙型肝炎绝大部分可以恢复,但有少数发展成为慢性肝炎,甚至引起肝硬变和肝癌.目前尚无一种可靠指标预测哪一部分HBV急性感染病人会进展成为慢性肝炎.据认为,高滴度HBsAg/IgM复合物是急性HBV感染者慢性化的危险因素之一.作者建立了检测血清中HBsAg/IgM复合物的简易放射免疫测定法(RIA),
Most adult acute hepatitis B can be restored, but a few develop into chronic hepatitis, and even cause cirrhosis and liver cancer.At present, there is no reliable index to predict which part of HBV acute infection patients will progress to become chronic hepatitis.Accordingly, High-titer HBsAg / IgM complex is one of the risk factors of chronic HBV infection.The authors established a simple radioimmunoassay (RIA) to detect HBsAg / IgM complex in serum,