目的　分析肝性脑病的诱因，探讨其诱因与预后的关系。方法　对本院收治的１４６ 例肝性脑病患者的临床资料进行回顾性分析。结果　肝性脑病的诱因依次为医源性因素（ 包括手术、利尿、放腹水、输血、药物）７６ 例（５０ ％ ） ，上消化道出血６７ 例（４５－９ ％ ） ，感染６２ 例（４２－５ ％ ） ，电解质紊乱５２ 例（３５－６ ％ ） ，肾功能不全３３ 例（２２－６ ％ ） ，腹泻６ 例（４－８ ％ ） ，饮食不节６ 例（４－８ ％ ） 。诱因的多少、严重程度与肝性脑病的发生发展及预后密切相关。结论　积极去除诱因是治疗肝性脑病的关键 Objective To analyze the causes of hepatic encephalopathy and explore its relationship with the prognosis. Methods The clinical data of 146 patients with hepatic encephalopathy admitted to our hospital were analyzed retrospectively. Results The predisposing factors of hepatic encephalopathy were iatrogenic factors (including surgery, diuretic, ascites, transfusions and drugs) in 76 cases (50%), upper gastrointestinal bleeding in 67 cases -5%), electrolytes disorder in 52 cases (35-6%), renal dysfunction in 33 cases (22-6%), diarrhea in 6 cases (4-8%), and diet irregularities in 6 cases (4-8%). The number of incentives, the severity of the occurrence and development of hepatic encephalopathy and prognosis are closely related. Conclusion It is the key to treat hepatic encephalopathy by actively removing the causes