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作者使用0.5～1.0％争光霉素软膏(BLM-O)治疗37例皮肤恶性肿瘤,结果如下: 1.癌前期17例(原位癌8例、老年性角化瘤2例、放射性角化病2例、阴部湿疹样癌3例、继发于着色性干皮病的赘疣状肿瘤2例),除阴部湿疹样癌外,全部取得了优异的成绩,显效率87.5％以上,一般显效的病例经过2年以上观察未看到复发。 2.皮肤癌12例,包括鳞状细胞癌7例,基底细胞癌5例,前者显效率为14.3％,后者为40％。基底细胞癌1～2级的表浅性病灶单独使用本法有治愈的可能性,鳞状细胞癌1级的表浅性病灶也确认是本法良好的适应症。
The authors treated 37 cases of cutaneous malignant tumors with 0.5 to 1.0% bleomycin ointment (BLM-O). The results were as follows: 1. Precancerous lesions in 17 cases (8 in situ carcinomas, 2 keratinomas, and radioactive keratoses) 2 cases, 3 cases of pudendal eczema-like carcinoma, and 2 cases of verrucous tumor secondary to xeroderma pigmentosum). Except for genital eczema-like carcinoma, all had excellent results with a markedly effective rate of 87.5% or more. After 2 years of observation, no recurrence was seen in the case. 2. 12 cases of skin cancer, including 7 cases of squamous cell carcinoma, 5 cases of basal cell carcinoma, the former significant efficiency of 14.3%, the latter 40%. Superficial lesions of grade 1 to 2 of basal cell carcinoma have the possibility of being cured using this method alone, and superficial lesions of grade 1 squamous cell carcinoma are also confirmed to be good indications of this method.