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作者以1976-1980年间日本久留米大学第二内科收治的30例DIC病例为研究对象,作多项诊治参数分析。基础疾患7例系临床诊断,23例为病理学诊断。包括恶性肿瘤12例,血液疾患9例,肝脏疾患4例,败血症3例及其他疾病2例。12例恶性肿瘤均于活检或临床上见有转移灶。5年间收治484例肝硬化患者中有3例(0.62%)发生DIC。出血倾向和脏器症状出血倾向见于多数病例,以皮下出血斑(24例)、消化道出血(11例)及齿龈出血(10例)多见。脏器症状中3例有脑血栓,2例有肾功能不全,2例有肝功能异常,足趾血栓症1例。微血管病性溶血性贫血(MHA)4例,均为恶性肿瘤的病例。
The author studied 30 DIC cases admitted to the Second Internal Medicine Department, University of Kurume, Japan in 1976-1980 for the analysis of a number of diagnosis and treatment parameters. Seven cases of underlying disease were diagnosed clinically and 23 cases were pathologically diagnosed. Including 12 cases of malignant tumors, 9 cases of blood disorders, liver disease in 4 cases, 3 cases of sepsis and other diseases in 2 cases. All 12 malignant tumors had metastases on biopsy or clinics. DIC occurred in 3 of 484 cirrhotic patients (0.62%) over 5 years. Bleeding tendency and visceral bleeding tendency found in most cases, with subcutaneous bleeding spots (24 cases), gastrointestinal bleeding (11 cases) and bleeding gums (10 cases) more common. Three cases of organ symptoms were thrombosis, two cases of renal insufficiency, two cases of liver dysfunction, toe thrombosis in 1 case. 4 cases of microangiopathy hemolytic anemia (MHA), all cases of malignant tumors.