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ｐ５３基因突变是人类恶性肿瘤中最常见的基因变化〔１〕，已有实验证明ｐ５３基因突变与结直肠的腺瘤癌变有关，而且与肿瘤的进展有关〔２〕。我们用免疫组织化学方法检测大肠癌肿瘤组织中ｐ５３基因表达情况，以探讨ｐ５３基因表达与大肠癌病理因素之间的关系。１材料...
The p53 gene mutation is the most common gene mutation in human malignant tumors [1]. Experiments have shown that p53 gene mutation is related to colorectal adenoma carcinogenesis and is related to tumor progression [2]. We used immunohistochemistry to detect the expression of p53 gene in colorectal cancer tumor tissues to explore the relationship between p53 gene expression and pathological factors of colorectal cancer. 1 material...