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目的通过对33例广州管圆线虫病患者的临床特点进行分析,提高临床医师对广州管圆线虫病的认识。方法分析33例广州管圆线虫病的流行病学调查资料、临床特征、实验室资料及治疗效果。结果发病前均有生食淡水螺肉或生鱼片史,潜伏期1～41 d。以头痛、躯体痛为主要表现,而无脑膜刺激征。周围血象、脑脊液中嗜酸粒细胞明显增高,用阿苯达唑治疗效果好,及时合理治疗预后良好。结论广州管圆线虫病主要累及中枢神经系统,阿苯达唑是有效的治疗药物。应早期诊断,及时报告,尽早合理用药,减少误诊。
Objective To analyze the clinical features of 33 cases of angiostrongyliasis in Guangzhou and improve their understanding of angiostrongylus cantonensis in Guangzhou. Methods The epidemiological survey data, clinical features, laboratory data and therapeutic effects of 33 cases of angiostrongyliasis in Guangzhou were analyzed. Results Before the onset of raw freshwater snails or sashimi history, the incubation period of 1 ~ 41 d. Headache, somatic pain as the main performance, but no signs of meningeal irritation. Peripheral blood, cerebrospinal fluid eosinophilia was significantly higher with albendazole treatment effect, timely and reasonable treatment of a good prognosis. Conclusion Angiostrongyliasis mainly affects the central nervous system and albendazole is an effective therapeutic drug. Should be diagnosed early, timely reporting, rational drug use as soon as possible to reduce misdiagnosis.