垂体前叶分泌GH呈脉冲式,且在睡眠慢波期达最大量。当前常用的GH缺乏症筛选试验就是根据这个观察而定的,因此需要整夜进行试验;白天试验则GH分泌易受药物等刺激所影响。无论是白天或夜间试验都需反复插管取血标本,故费时,耗资,占据病床,且使病人自觉不适和有一定危险 GH secretion of the anterior pituitary gland is pulsatile, and sleep up to the maximum amount of sleep. The currently used GH deficiency screening test is based on this observation and therefore requires an overnight test; during the day, GH secretion is susceptible to stimuli such as drugs. It is time-consuming, costly, occupying a hospital bed, and makes the patient consciously uncomfortable and at certain risk, both during the daytime or nighttime test.