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目的:探讨多种西药合用的不良反应及促进西药临床合理用药。方法:选择我院2013年7月-2015年7月门诊处方2308份,回顾性分析者2308份西药的配伍情况,并记录患者服用药物后出现的不良反应情况。结果:本次接受调查的2308份西药配伍处方中,总计出现87份药方引发患者不良反应。其中23例患者表现为恶心、呕吐、16例患者存在头昏、24例患者存在发热、乏力、43例患者存在失眠、兴奋、31例患者出现皮疹、11例患者出现水肿;同时,部分患者同时存在多种不良反应合并情况,极少数患者伴有心功能损害和肾功能衰竭的情况。导致不良反应的原因有很多,当多种西药联用出现用法不当、重复用药或给药剂量失误时引发不良反应的几率更高。结论:西药的种类有很多,不同药物合用可能引发一定的不良反应。因此,在实际使用时,要保证合理的西药合用才能降低药物使用的不良反应,提高疗效的同时,保证患者满意度。
Objective: To explore the adverse reactions combined with western medicine and to promote the clinical rational use of western medicine. Methods: We selected 2308 outpatient prescriptions from July 2013 to July 2015 in our hospital, retrospectively analyzed the compatibility of 2,308 western medicines and recorded the adverse reactions of patients after taking the drugs. Results: Of 2308 western medicine prescriptions investigated in this survey, a total of 87 prescriptions caused adverse reactions in patients. Among them, 23 patients showed nausea and vomiting, 16 patients had dizziness, 24 patients had fever and fatigue, 43 patients had insomnia, excitement, 31 patients had a rash and 11 patients had edema. At the same time, some patients There are many adverse reactions combined situation, very few patients with cardiac dysfunction and renal failure. There are many reasons that lead to adverse reactions, when a variety of western medicine appear improperly used, repeated medication or dosage error when the risk of adverse reactions caused by a higher probability. Conclusion: There are many kinds of western medicine, different drugs may trigger some adverse reactions. Therefore, in actual use, to ensure that reasonable combination of Western medicine can reduce the adverse drug reactions, improve the efficacy, while ensuring patient satisfaction.