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随着人们对原发性血小板减少性紫癜(ITP)发病机理研究的逐步深入,抗血小板(Pt)抗体的病理作用已基本得到确认。血小板相关IgG(PAIgG)的测定业已成为诊断ITP的一项重要指标。本文拟就目前常用检测PAIgG的方法、PAIgG对ITP诊断的价值、对病情、疗效的估价及它在其它疾病中的意义作一综述。一、PAIgG的主要检测方法对ITP患者抗体的检测,最初主要测定血清中抗Pt抗体,但因其阳性率不高(60%左
With the gradual deepening of the research on the pathogenesis of idiopathic thrombocytopenic purpura (ITP), the pathological effects of anti-platelet (Pt) antibodies have been basically confirmed. Determination of platelet-associated IgG (PAIgG) has become an important indicator of ITP diagnosis. This article is about the commonly used methods of detecting PAIgG, the value of PAIgG in diagnosing ITP, the evaluation of the condition and curative effect and its significance in other diseases. First, the main test of PAIgG Detection of antibodies to ITP patients, the initial determination of serum anti-Pt antibody, but its positive rate is not high (60% of the left