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特应症是指针对环境中无害抗原(变应原,如尘螨、花粉等)的一种变态反应,如哮喘、枯草热和湿疹,其特点为血清中有变应原特异性的IgE及针对变应原的皮肤试验阳性。已知Th1 、Th2细胞亚群和它们分泌的细胞因子之间存在着桔抗作用。由Th2细胞亚群所产生的细胞因子如IL-4、IL-10、IL-13,在介导IgE合成及速发型变态反应中起着重要作用。在日本学童中的调查研究发现,迟发性的旧结核菌素(OT)变态反应与特应症之间存在明显的负相关。OT反应阳性者
Atopy refers to an allergic reaction to environmentally harmful antigens (allergens such as dust mites, pollens, etc.), such as asthma, hay fever and eczema, characterized by allergen-specific IgE in the serum And positive skin tests for allergens. It is known that Th1, Th2 cell subsets and their secretion of cytokines exist between the anti-orange role. Cytokines such as IL-4, IL-10 and IL-13 produced by Th2 cell subsets play an important role in mediating IgE synthesis and immediate-onset allergic reactions. In a study of Japanese schoolchildren, there was a clear negative correlation between late-onset old tuberculin (OT) allergy and atopy. OT reaction positive person