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目的分析上海市长宁区2008年麻疹-流行性腮腺炎-风疹联合减毒活疫苗(Measles,Mumps,RubellaCombined Attenuated Live Vaccine,MMR)预防接种不良事件(Adverse Events Following Immunization,AEFI),研究监测的有效模式,为建立规范化预防接种安全监测体系提供依据。方法以MMR作为监测疫苗,采用主动监测与被动监测相结合的方法开展AEFI监测研究。结果收集AEFI报告95例,多为一般反应;主动监测模式获得的AEFI信息明显多于被动监测;各级疾病预防控制中心建立了信息沟通交流机制。结论主动与被动相结合的监测模式,可提高AEFI报告的敏感性和利用率。
OBJECTIVE: To analyze the effectiveness of measles, mumps and rubella combinated Attenuated Live Vaccine (MMR) vaccination adverse events (AEFI) in 2008 in Changning District, Shanghai Model, to establish a standardized vaccination safety monitoring system to provide the basis. Methods MMR was used as a surveillance vaccine and the AEFI monitoring study was conducted by a combination of active surveillance and passive surveillance. Results AEFI was collected in 95 cases, most of which were general reactions. The AEFI information obtained by the active monitoring model was significantly more than that of the passive monitoring. The CDC centers at all levels established an information communication mechanism. Conclusion The combination of active and passive monitoring models can increase the sensitivity and utilization of AEFI reporting.