Phosphoester modified poly（ethylenimine） as efficient and low cytotoxic genevectors

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：Ryan

【摘要】

：

Cyclic phosphoester monomer ethyl ethylene phosphate (EEP) modified poly(ethylenimine) (PEI),denoted as PEI-EEP,was developed for gene delivery.Three PEI-EEP po

【作者】

：

DU JinZhi TANG LingYan YUAN Yo

【机构】

：

DepartmentofPolymerScienceandEngineering,HefeiNationalLaboratoryforPhysicalSciencesatMicroscaleandSc

【出处】

：

中国科学：化学英文版

【发表日期】

：

2011年2期

【关键词】

：

亚胺改性低毒性 Zeta电位转染效率核磁共振方法 HeLa细胞 HEK293 gene delivery PEI phosphoester gen

【基金项目】

：

This work was supported by the National Basic Research Program of China （973 Program, 2010CB934001）.

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Cyclic phosphoester monomer ethyl ethylene phosphate (EEP) modified poly(ethylenimine) (PEI),denoted as PEI-EEP,was developed for gene delivery.Three PEI-EEP polymers were synthesized and their structures were characterized by 1H and 31P NMR methods.All t

其他文献

Optical scheme for realization of optimal unambiguous state discrimination of the JS limit

We exploit optimal probabilistic cloning to rederive the JS limit.Dependent on the formulation given by the optimal probabilistic cloning,the explicit transform

期刊

状态成功概率光学器件研究所量子态非正交克隆quantum state discrimination optimal unambiguous di

Photochemical hydrogen production with molecular devices comprising a zinc porphyrin and a cobaloxi

二新 noble-metal-free 分子的设备，[{公司( dmgH ) 2Cl }{ Zn ( PyTPP )}]( 1 ， dmgH = dimethyloxime ， PyTPP =5-( 4-pyridyl )-10,15,20-triphenylporphyrin)并且[{公司( dm

期刊

光化学分子器件钴催化剂锌卟啉分子内电子转移产氢气相色谱分析荧光猝灭可见光照射cobaloxime hydrogen production m

Epoxidation of olefins with hydrogen peroxide catalyzed by a reusable lacunary-type phosphotungstate

石蜡和 allylic 白酒用阶段转移催化剂是有商业地可得到的氢过氧化物(30% H2O2 ) 的 epoxidized， cetyltrimethylammonium 阳离子和一个 lacunary 类型 phosphotungstate 阴离

期刊

磷钨酸催化剂烯烃环氧化过氧化氢可重复使用缺位氢催化杂多阴离子相转移催化剂heteropolyphosphotungstate lacunary

An inverted triplesalen ligand by a convergent synthesis and its influence on trinuclear FeⅢ3 compl

The inverted triplesalen ligand H 6 feld Me has been synthesized from 2,4,6-triformyl-phloroglucinol and a ketimine salen half-unit in a convergent synthesis. N

期刊

三核配合物氯化铁复合物合成收敛反铁磁相互作用单晶X-射线衍射紫外可见光谱magnetic properties iron complexes

Anharmonic vibrations of nucleobases： Structural basis of one-and two-dimensional infrared spectra f

错配的底配对的正规 Watson 痛性痉挛基础对和四个代表被量化学药品计算学习了。详细非谐的震动的分析被执行揭示基础单体和 dimers 的结构的方面的某震动的签名特征，它很好在

期刊

二维红外光谱非谐振动光谱结构碱基对不匹配量子化学计算振动分析能量分布quantum chemical computation canonical

Luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline indole complexes as biological probes

Four luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline complexes appended with an indole moiety [Ir(N^C)2(N^N)] (PF6) (HN^C = 2-phenylpyridine, Hppy; N

期刊

BINDINGINDOLEIRIDIUMLUMINESCENCEprobesbindingindoleiridiumluminescenceprobe

Synthesis,structure and photoluminescence of two porous metal-organoboron frameworks with rtl topolo

僵硬三角的 tris ( 3-pyridylduryl ) borane L 从容易地可得到的 1,2,4,5-tetramethylbenzene 在好全面产量通过四步被综合并且被用来构造二多孔的镉( II )建筑群 Cd (L) X

期刊

多孔金属拓扑结构光致发光有机硼RTL合成镉(Ⅱ)配合物框架boron metal-organic frameworks coordination

Polycyclic aromatic hydrocarbons in the centralized wastewater treatment plant of a chemical indust

增加的注意被给了象多不的芳香的烃那样的污染物质的命运(哼) 介绍给废水处理植物。溶解并且吸附哼在浙江省在一个化学工业地区的集中的废水处理植物被检测，中国。最丰富哼低

期刊

污水处理厂多环芳烃化学工业区质量平衡微生物吸附超高分子量好氧生物处理好氧生物工艺polycyclic aromatic hydrocarbons

Structural properties of hydroxyl-substituted alkyl benzenesulfonates at the water/vapor and water/d

分子的动力学模拟被执行了调查在水 / 蒸汽和 water/decane 接口形成的代替氢氧根的烷基 benzenesulfonate 单层的结构的性质。我们报导界面的 propertiesliquid 密度侧面，氢

期刊

取代烷基结构特性外部接口阴离子表面活性剂疏水羟基蒸汽分子动力学模拟molecular dynamics hydroxyl-substitute

Effects of charge distribution on water filling process in carbon nanotube

Using umbrella sampling technique with molecular dynamics simulation,we investigated the nanoflu-idic transport of water in carbon nanotube(CNT).The simulations

期刊

NANOTUBEmicro/nanofluidicMOLECULARDYNAMICSnanotube micro/nanofluidic molecul

Phosphoester modified poly（ethylenimine） as efficient and low cytotoxic genevectors

与本文相关的学术论文