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目的 探讨α1-酸性糖蛋白检测在类风湿性关节炎 (RA)活动性评估中的意义。方法 对 30例活动期患者和 16例非活动期患者 α1-酸性糖蛋白检测 ,并与正常人比较。结果 活动期患者 α1-酸性糖蛋白明显高于非活动期患者 ,且两者均高于正常人 (P <0 .0 0 1)。活动期组 8例患者治疗后 α1-酸性糖蛋白明显下降 (P <0 .0 5 ) ,但仍高于正常人 (P <0 .0 5 )。结论 α1-酸性糖蛋白检测在活动期评估中有一定临床价值
Objective To investigate the significance of α1-acid glycoprotein in assessing the activity of rheumatoid arthritis (RA). Methods The α1-acid glycoprotein in 30 active patients and 16 inactive patients was detected and compared with normal subjects. Results The activity of α1-acid glycoprotein in patients with active phase was significantly higher than inactive patients, and both were higher than normal (P <0.01). The activity of α1-acid glycoprotein was significantly decreased in 8 active patients (P <0.05), but still higher than that in normal subjects (P <0.05). Conclusion α1-acid glycoprotein detection in the evaluation of active phase has some clinical value