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目的了解2009—2011年山东省乡镇卫生院抗生素药品消耗情况,为农村地区开展抗生素合理使用促进工作提供相关政策建议。方法按随机抽样原则在山东省3县区9所乡镇卫生院收集2009—2011年的药品出库资料,通过ATC/DDD方法对抗生素类药品的销售金额和用药频度(DDDs)及二者的年平均增长率(AARG)进行分析,并进一步分析DDDs排名前20位药品的日均费用(DDDc)情况。结果 2009—2011年抗生素类药品销售金额和DDDs年平均增长率分别为-6.92%和3.76%;各年度第三代头孢菌素类抗生素的销售金额均居首位,其AARG为11.46%,而DDDs各年均居首位的是广谱青霉素类,其AARG为10.67%;抗生素类药品的DDDc总体上呈下降趋势,阿莫西林、阿奇霉素和头孢氨苄是乡镇卫生院最常使用的抗生素药品。结论基本药物制度实施后抗生素销售金额呈现下降趋势,但用药频度仍然呈现增长趋势,且广谱类抗生素是乡镇卫生院使用最主要的抗生素类型。
Objective To understand the consumption of antibiotics in township hospitals in Shandong province from 2009 to 2011 and provide relevant policy recommendations for promoting the rational use of antibiotics in rural areas. Methods According to the principle of random sampling, the data of drug release from 2009 to 2011 were collected from 9 township hospitals in 3 counties of Shandong Province. The sales volume and frequency of antibiotics (DDDs) and the Annual average growth rate (AARG) analysis, and further analysis of DDDs ranked the top 20 drugs daily average cost (DDDc) situation. Results The sales volume of antibiotics and the average annual growth rate of DDDs in 2009-2011 were -6.92% and 3.76%, respectively. The sales amount of the third generation cephalosporins in each year was the highest, with the AARG of 11.46% DDDs ranked the first place in each year is broad-spectrum penicillins, the AARG was 10.67%; DDDc antibiotics generally showed a downward trend, amoxicillin, azithromycin and cephalexin are the most commonly used antibiotics in township hospitals. Conclusions After the implementation of the basic drug system, the sales volume of antibiotics shows a downward trend, but the frequency of drug use still shows an increasing trend. And broad-spectrum antibiotics are the most important types of antibiotics used by township hospitals.