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目的:了解我院药品不良反应(ADR)发生的一般规律及特点。方法:对我院2007年1月～2009年6月收集到的286例填报完整和有分析评价的ADR报告表进行统计、分析。结果:严重的ADR有3例;我院抗感染药的ADR居首位,有213例(占74.48%),其次为中药制剂,有38例(13.29%);ADR的临床表现以皮肤及其附件损害为主,有146例(占44.92%),其次为消化系统损害,有62例(占19.08%);静脉滴注最易导致ADR,有202例(占70.63%)。结论:建立与完善药物使用的监督与管理制度,重视ADR监测,可减少我院ADR的发生。
Objective: To understand the general rules and characteristics of adverse drug reaction (ADR) in our hospital. Methods: A total of 286 ADR reports completed and analyzed by our hospital from January 2007 to June 2009 were collected for statistical analysis. RESULTS: There were 3 cases of severe ADR. The ADR of anti-infectives in our hospital ranked the first with 213 cases (74.48%) followed by traditional Chinese medicine preparations (38 cases, 13.29%). The clinical manifestations of ADR were as follows: There were 146 cases (accounting for 44.92%), followed by digestive system damage, 62 cases (19.08%). The most likely cause of ADR was intravenous drip, with 202 cases (70.63%). Conclusion: Establishing and perfecting the supervision and management system of drug use and attaching importance to ADR monitoring can reduce the occurrence of ADR in our hospital.