含醇的药物制剂如酊剂、流浸膏、醑剂、酏剂等等,各国药典对其含醇量多有规定,并作为重要的质量指标之一。多少年来含醇量的測定一直沿用蒸餾法作为法定方法。苏联药典第九版始有沸点法收载,說明可作为酊剂的含醇量测定。但蒸餾法測定醇含量需时长,手續繁,結果不够准确(准确度±2%),且在蒸餾过程中常有泡沫及突沸現象,检品中有甘油、碘、揮发油、揮发性溶媒、氨等存在时还需在蒸餾前后作特 Alcohol-containing pharmaceutical preparations such as tinctures, flow extracts, tinctures, tinctures, etc., are prescribed by various national pharmacopoeias for their alcohol content, and are one of the important quality indicators. For many years the determination of alcohol content has been based on distillation as a statutory method. The ninth edition of the Soviet Pharmacopoeia was initially included in the boiling point method to indicate the amount of alcohol that can be used as a tanning agent. However, the determination of alcohol content by distillation method takes a long time, and the procedure is complicated. The result is not accurate enough (accuracy ±2%), and there are often bubbles and bumps in the distillation process. There are glycerin, iodine, volatile oil, and volatile solvent in the sample. , ammonia, etc. also need to be special before and after distillation