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目的:分析晚期妊娠宫内感染的发病原因及其对母婴健康的影响。方法:将2015年9月至2017年2月于中山市博爱医院确诊为晚期妊娠宫内感染的患者60例作为研究对象,将其按照分娩孕周的长短分为早产组和足月组各30例,比较两组患者宫内感染的诊断时间点,对两组宫内感染病例破膜情况进行比较,比较两组破膜情况及分娩方式,对两组母婴预后效果进行比较,并对两组胎盘病理检查结果进行比较。结果:早产组入院时和期待中确诊率明显高于足月组,引产中和产程中确诊率明显低于足月组,差异具有统计学意义(P<0.05)。早产组胎膜早破发生率较足月组明显更高,差异具有统计学意义(P<0.05)。但两组胎膜自破、胎膜未破发生率和剖宫产率比较,差异无统计学意义(P>0.05);早产组产褥感染、新生儿感染和围生儿死亡发生率均明显高于足月组,差异具有统计学意义(P<0.05)。两组产妇胎盘绒毛膜羊膜炎Ⅲ级比较,差异无统计学意义(P>0.05);早产组绒毛膜羊膜炎Ⅱ级比例明显高于对照组,并且早产组病理检查阴性率明显低于足月组,差异具有统计学意义(P<0.05)。结论:晚期妊娠宫内感染会对母婴预后造成严重影响,严重时危及母婴生命安全,在妊娠过程中应加强对宫内感染的鉴别诊断,并在确诊时及时采取有效的治疗措施,从而确保母婴安全。
Objective: To analyze the causes of intrauterine infection in late pregnancy and its effect on maternal and infant health. Methods: From September 2015 to February 2017, 60 cases of intrauterine infection of late pregnancy diagnosed in Pok Oi Hospital of Zhongshan were studied. According to the gestational weeks of birth, they were divided into preterm group and term group Cases of intrauterine infection in both groups were compared at the time point of diagnosis of intrauterine infection in the two groups of cases of rupture of membranes compared the situation of rupture of membranes and delivery mode, the two groups were compared the prognosis of maternal and infant, and two Group placenta pathological examination results were compared. Results: The diagnosis rate of preterm delivery group was significantly higher than that of term group at the time of hospitalization and expectation. The diagnosis rate of midwifery and labor was significantly lower than that of term group (P <0.05). Premature rupture of membranes premature rupture of the incidence was significantly higher than the full-term group, the difference was statistically significant (P <0.05). However, there was no significant difference between the two groups (P> 0.05). The incidence of puerperal infection, neonatal infection and perinatal mortality were significantly higher in preterm labor group Higher than the full-term group, the difference was statistically significant (P <0.05). The placental chorioamnionitis between the two groups showed no significant difference in grade Ⅲ (P> 0.05). The percentage of chorioamnionitis in preterm group was significantly higher than that in control group, and the negative rate of pathological examination in preterm group was significantly lower than that in term group Group, the difference was statistically significant (P <0.05). Conclusion: Intrauterine infection in late pregnancy will have a serious impact on the prognosis of maternal and infant. In severe cases, it may endanger maternal and infant life safety. In the course of pregnancy, differential diagnosis of intrauterine infection should be strengthened and effective treatment should be taken timely Make sure mother and baby are safe.