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目的：探讨质子泵抑制剂奥美拉唑治疗胃溃疡合并出血的临床价值。方法治疗组用质子泵抑制剂注射用奥美拉唑治疗胃溃疡合并出血，对照组用H2受体拮抗剂注射用法莫替丁治疗。结果质子泵抑制剂奥美拉唑疗效明显优于H2受体拮抗剂法莫替丁。结论质子泵抑制剂用于胃溃疡合并出血疗效可靠。“,”Objective To explore the clinical effects of omeprazole used for patients with gastric ulcer combined with bleeding.Methods Control group was added with therapy of famotidine, and experimental group was added with therapy of omeprazole .Results:Omeprazole used for patients with gastric ulcer combined with bleeding was superior to H2 receptor antagonist famotidine.ConclusionOmeprazole used for patients with gastric ulcer combined with bleeding can guarantee the safety.