论文部分内容阅读
目的观察成人Still病的临床特点,提高对此疾病的认识。方法回顾分析从2007年1月-2009年12月收治的12例成人Still病患者的临床资料,观察其临床特点。结果 12例患者体温均≥39.0℃,有一过性皮疹、关节疼痛,周围血常规白细胞总数、中性粒细胞增高(白细胞≥15.0×109/L、中性粒细胞≥80%),血沉、C-反应蛋白、血清铁蛋白增高,骨髓涂片为增生性骨髓像,其次有咽痛,肝、脾、淋巴结肿大等临床表现。糖皮质激素是治疗的主要措施。结论成人Still病临床表现复杂多样,实验室检查缺乏特异性,血清铁蛋白检测值的明显增高有助于诊断。患者经糖皮质激素治疗后预后效好。
Objective To observe the clinical features of adult Still disease and to raise awareness of the disease. Methods The clinical data of 12 adult Still disease patients admitted from January 2007 to December 2009 were retrospectively analyzed. The clinical features were observed. Results All 12 patients had a temperature of ≥39.0 ℃. They had transient rash, joint pain, total leukocytes in peripheral blood, neutrophils (≥15.0 × 109 / L for leukocytes, ≥80% for neutrophils), erythrocyte sedimentation rate - Reactive protein, serum ferritin increased bone marrow smears for proliferative bone marrow, followed by sore throat, liver, spleen, lymph nodes and other clinical manifestations. Glucocorticoid is the main treatment. Conclusion The clinical manifestations of adult Still disease are complex and diverse, the laboratory tests lack specificity and the serum ferritin test value is obviously increased, which is helpful for the diagnosis. Patients with good prognosis after glucocorticoid treatment.