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利用基因免疫技术以验证ＨＰＶ１６（湖北株）Ｅ７基因在体内的表达状况及抗原性，为进一步发展有效的疫苗或治疗性制剂提供理论依据。取ＢＡＬＢ／ｃ小鼠２３只，随机分为３组，１５只注射含Ｅ７基因编码框的重组质粒ｐＬ（Ｅ７－ＨＢ）ＳＮ１００μｇ／１００μｌ，４只...
The use of gene immunization technology to verify HPV16 (Hubei strain) E7 gene expression in vivo and antigenicity, to provide a theoretical basis for the further development of effective vaccine or therapeutic preparations. Twenty-three BALB / c mice were randomly divided into three groups. Fifteen mice were injected with recombinant plasmid pL (E7-HB) SN100μg / 100μl containing E7 gene coding sequence