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1976年Shamberger等报道,美国大肠癌死亡率随饲料作物硒含量的增高而降低,19个地区的居民全血硒浓度与肿瘤死亡呈显著负相关。同年Schrauzer指出,大肠和乳腺癌的死亡率与膳食中硒摄取量有关,他分析了20多个国家的有关资料,证明硒摄取量或血硒水平与大肠癌、乳腺癌、前列腺癌和白血病之间具有非常显著的负相关。浙江省嘉善县为我国大肠癌高发区,1974～76年大肠癌标化死亡率男23.61/10万,女
In 1976, Shamberger et al. Reported that the mortality rate of colorectal cancer in the United States decreased with the increase of the selenium content in feed crops. There was a significant negative correlation between the serum selenium concentration of residents in 19 districts and tumor death. In the same year Schrauzer pointed out that the mortality rate of colorectal and breast cancer is related to dietary selenium intake. He analyzed relevant data from more than 20 countries and showed that the selenium intake or selenium level is associated with colorectal cancer, breast cancer, prostate cancer and leukemia There is a very significant negative correlation between. Jiashan County, Zhejiang Province, China’s high incidence of colorectal cancer, colorectal cancer in 1974 to 76 years, the standardized mortality rate of male 23.61 / 100000, female