近十年来国外对于黄酮类化合物的类似物——2-或3-杂环色酮的生理活性产生了极大兴趣,例如探索了具有抗癌活性的8-羧甲基黄酮的类似物2-(2-呋喃;2-噻吩)-8-羧甲基色酮的抗癌活性,以及发现了2-(3-吡啶)-6,8-二氯色酮具有驱虫作用。本文作为研究杂环色酮构效关系的一部分,首先合成了心血管药物立可定——7-乙氧羰甲氧基黄酮的类似 In recent ten years abroad, the analogues of flavonoids, 2-or 3-heterocyclic chromone have great interest in the physiological activity, for example, has explored the anti-cancer activity of 8-carboxymethyl flavone analog 2- (2-furan; 2-thiophene) -8-carboxymethylchromone and its anthelminthic activity was found to be 2- (3-pyridyl) -6,8-dichlorochromone. In this paper, as part of the study of the structure-activity relationship of heterocyclic chromones, we first synthesized the analogs of 7-ethoxycarbonylmethoxyflavone