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本文报道采用Iodogen法以~(131)I标记的抗人结肠癌McAbs SC3A,在荷人结肠癌裸鼠体内的生物学分布及放射免疫定位显像研究的结果。McAb SC3A腹水经protein ASepharose 4B纯化后,SDS-PAGE电泳鉴定纯度,分子量为160kD。标记结果标记率在85％以上,放化纯度在95％以上。用同法
This paper reports the biological distribution and radioimmunolocalization imaging results of anti-human colon cancer McAbs SC3A labeled with 131I in the nude mice using Iodogen method. McAb SC3A ascites was purified by protein ASepharose 4B and purified by SDS-PAGE. The molecular weight was 160 kD. Marked result marking rate is above 85% and radiochemical purity is above 95%. Using the same method