【摘 要】
：
A simple and metal-free method has been developed for the construction of quinoline-2,4-carboxylates under mild conditions via a molecular iodine-catalyzed thre
【机 构】
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College of Chemistry and Biology, Xinjiang Laboratory of Phase Transitions and Microstructures of Co
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
A simple and metal-free method has been developed for the construction of quinoline-2,4-carboxylates under mild conditions via a molecular iodine-catalyzed three-component tandem reaction of arylamines, ethyl glyoxylate, and a-ketoesters. The present protocol provides a convenient and attractive approach to various quinoline-2,4-carboxylates in moderate to good yields with excellent functional group tolerance.
A simple and metal-free method has been developed for the construction of quinoline-2,4-carboxylates under mild conditions via a molecular iodine-catalyzed three-component tandem reaction of arylamines, ethyl glyoxylate, and a-ketoesters. The present protocol provides a convenient and attractive approach to various quinoline-2,4-carboxylates in moderate to good yields with excellent functional group tolerance.
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