药物进入人体后,绝大多数借助血液到达作用部位或受体部位。大多数药物的治疗和毒性作用的强度,则取决于作用部位或受体部位的浓度,而药物到达作用部位的浓度与血药浓度直接有关;药物在血液中的浓度变化常可反映作用部位的浓度变化,故血药浓度的测定对临床合理用药,安全用药,有效用药具有重大的意义。 After the drug enters the body, the vast majority of the blood reaches the site of action or receptor. The intensity of the therapeutic and toxic effects of most drugs depends on the concentration of the site of action or the site of the receptor, and the concentration of the drug reaching the site of action is directly related to the plasma concentration; the change of the concentration of the drug in the blood can often reflect the site of action Concentration changes, so the determination of plasma concentration of clinical rational drug use, safe medication, effective medication is of great significance.