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目前市售的土霉素片大部分是糖衣片,最近西安制药厂试制了薄膜片。薄膜片与糖衣片相比,具有省料、省时和包衣均匀等优点。但两者哪种溶出度高,尚未见有资料报导。为此,我们进行了试验,现报告如下: 实验部分一、仪器、试剂与样品仪器:(1)80型药物释放度测定仪(数字显示转速),江苏武进县精密仪器厂。 (2)崩解仪BJY-63型 (3)WFZ800-D_2型紫外-可见分光光度计,北京第二光学仪器厂。试剂:0.1 M盐酸溶液。样品:土霉素薄膜片(0.25g/片)西安制
Most oxytetracycline tablets currently on the market are sugar-coated tablets, the recent trial of Xi’an Pharmaceutical Factory film. Film and sugar-coated film compared with the material saving, time-saving and uniform coating and so on. However, both the dissolution rate is high, no data have been reported. To this end, we conducted the experiment, are reported as follows: Experimental part First, equipment, reagents and sample equipment: (1) 80 drug release tester (digital display speed), Jiangsu Wujin Precision Instrument Factory. (2) disintegration instrument BJY-63 type (3) WFZ800-D_2 UV-visible spectrophotometer, Beijing Second Optical Instrument Factory. Reagents: 0.1 M hydrochloric acid solution. Samples: oxytetracycline film (0.25g / tablet) Xi’an system