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【目的】探讨在体外受精‐胚胎移植（IVF‐ET ）治疗中采用超常方案降调节后分别使用尿源性卵泡刺激素（u‐FSH）和基因重组FSH（r‐FSH）联合尿促性腺激素（HMG）促排后的临床结局。【方法】回顾性分析2013年1～12本院生殖中心559例接受IVF或卵胞浆单精子注射（ICSI）助孕治疗的临床结局。【结果】两组患者促性腺激素（gonadotropin ，Gn）天数、Gn使用剂量，获卵数、受精率、卵裂率、妊娠率、可利用胚胎数、种植率、流产率、异位妊娠率、卵巢过度刺激综合征（OHSS）发生率均无显著差异（ P ＞0．05）。【结论】IVF‐ET中超长方案降调节后u‐FSH联合HMG和r‐FSH联合 HMG促排卵的效果相当。“,”[Objective] To compare the clinical efficacy of in vitro fertilization‐embryo transfer (IVF‐ET ) versus two different kinds of follicle‐stimulating hormone (FSH) stimulation protocols for controlled hyper‐stimulation after super‐long down‐regulation .[Methods]A total of 559 IVF/intracytoplasmic sperm injection (ICSI)‐ET cycles in in‐fertile patients at our reproductive center from January to November 2013 were analyzed retrospectively .According to the ovarian stimulation protocolr‐FSH+75IUHMG ,they were divided into two groups of gonal‐F ( n =294) and urofollitropin group ( n=265) .The clinical outcomes were compared between two groups .[Results]The total dos‐age of gonadotropin ,duration of gonadotropin stimulation ,estradiol level on HCG day ,number of retrieved oocytes , fertilization rate ,number of tranferable embryos ,clinical pregnancy rate ,implantation rate ,abortion rate ,rate of ec‐topic pregnancy and incidence of ovarian hyperstimulation syndrome were not significantly different between two groups ( P>0 .05) .[Conclusion]A combination of u‐FSH or r‐FSH and HMG have the same effectiveness in ovari‐an stimulation during IVF‐ET cycles after super‐long down‐regulation .