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目的 探讨腮腺炎脑膜脑炎患儿血清及脑脊液特异性IgM抗体检测的临床意义。 方法 对 97例临床诊断为腮腺炎脑膜脑炎患儿 ,应用酶联免疫吸附试验 (ELISA)方法检测血清及脑脊液特异性IgM抗体。结果 血清IgM抗体阳性率为 94 44 % (85 / 90 ) ,脑脊就座IgM抗体阳性率为 86 90 % (73/ 84)。结论 采用ELISA方法检测脑脊液腮腺炎病毒特异性IgM抗体是早期诊断腮腺炎脑膜脑炎的有效方法之一
Objective To investigate the clinical significance of detecting serum and cerebrospinal fluid specific IgM antibodies in mumps meningoencephalitis. Methods Serum and CSF specific IgM antibodies were detected in 97 children with mumps meningoencephalitis by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of IgM antibody in serum was 94 44% (85/90). The positive rate of IgM antibody in CSF was 86 90% (73/84). Conclusion It is an effective method to detect mumps meningoencephalitis by ELISA for the detection of cerebrospinal fluid mumps virus-specific IgM antibody