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目的观察腔镜辅助下手术与开放性手术治疗早期甲状腺癌的效果对比。方法选取2013年2月—2016年3月行手术治疗的早期甲状腺癌患者86例,按照手术方式不同,随机分为对照组42例,行开放性手术治疗;实验组44例,行腔镜辅助开放性手术治疗。观察两组术中及术后各项指标、手术治疗效果及术后回访1~3年生存率。计量资料比较采用t检验,计数资料比较采用χ2检验,P<0.05为差异有统计学意义。结果实验组手术时间(112.37±24.53)min、术后引流量(114.04±28.31)ml及拔管时间(5.78±1.07)min高于对照组[(54.36±5.76)min、(37.63±12.69)ml、(2.89±1.23)min],实验组术时出血量(57.69±5.63)ml、住院时间(7.45±1.02)d低于对照组[(83.77±10.26)ml、(8.56±1.87)d],比较差异有统计学意义(均P<0.05);实验组清除淋巴结数量、中央区淋巴结转移率及3年内复发率与对照组相比,差异无统计学意义(均P>0.05);实验组三年生存患者总生存率100%高于对照组97.61%,但差异无统计学意义(P>0.05)。结论腔镜下辅助手术治疗早期甲状腺癌效果佳,降低了术中出血量,缩短了住院时间。
Objective To compare the efficacy of endoscopic assisted surgery and open surgery in the treatment of early thyroid cancer. Methods Totally 86 patients with early thyroid cancer who underwent surgical treatment from February 2013 to March 2016 were randomly divided into control group (42 cases) and open surgery group (44 cases). The patients in the experimental group were assisted by open endoscopy Sexual surgery. The intraoperative and postoperative indicators, surgical treatment and postoperative follow-up of 1 to 3 years survival rate were observed. Measurement data were compared using t test, count data were compared using χ2 test, P <0.05 for the difference was statistically significant. Results The operation time (112.37 ± 24.53) min, postoperative drainage volume (114.04 ± 28.31) ml and extubation time (5.78 ± 1.07) min in the experimental group were significantly higher than those in the control group [(54.36 ± 5.76) min and (37.63 ± 12.69) , (2.89 ± 1.23) min in the experimental group, and 57.69 ± 5.63 ml in the experimental group and 7.45 ± 1.02 in the experimental group [(83.77 ± 10.26) ml, (8.56 ± 1.87) d, respectively] (P <0.05). There was no significant difference in the number of lymph nodes, the rate of lymph node metastasis in the central area and the recurrence rate in 3 years between the two groups (all P> 0.05) The overall survival rate of patients with survival was 100% higher than 97.61% of the control group, but the difference was not statistically significant (P> 0.05). Conclusions Endoscopic assisted surgery for early thyroid cancer is effective, reducing the amount of intraoperative bleeding and shortening the length of stay.