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目的:分析乌司他丁治疗慢性阻塞性肺病急性加重期的临床效果。方法:选择2012年1月到2013年12月来我院就诊的慢性阻塞性肺病急性加重期50例,随机分为2组,治疗组和对照组各25例,治疗组给予乌司他丁20万单位日三次静注,对照组按照慢性阻塞性肺疾病急性加重期的治疗指南给予常规治疗。结果:治疗组的总有效率为92.0%,对照组的总有效率为72.0%,两组有效率比较差异有统计学意义(P<0.05),两组患者治疗前后肺功能和炎症指标比较,差异有统计学意义(P<0.05)。结论:乌司他丁治疗慢性阻塞性肺病急性加重期的临床效果比较满意,临床应用价值较大。
Objective: To analyze the clinical effect of ulinastatin in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods: Fifty patients with chronic obstructive pulmonary disease (COPD) exacerbated from January 2012 to December 2013 in our hospital were randomly divided into two groups: 25 cases in each treatment group and control group. The patients in treatment group received ulinastatin 20 Thousands of units on the 3rd intravenous injection, the control group in accordance with the guidelines for the treatment of acute exacerbation of chronic obstructive pulmonary disease routine treatment. Results: The total effective rate of the treatment group was 92.0%, the total effective rate of the control group was 72.0%, the difference between the two groups was statistically significant (P <0.05). Before and after treatment, the lung function and inflammation indexes of two groups were compared, The difference was statistically significant (P <0.05). Conclusion: The clinical effect of ulinastatin in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) is satisfactory and its clinical value is great.