1987年来,我们对某化工厂生产对氮基苯酚工人的职业性皮炎进行了五年的观察和随访其原因与职业因素有关,兹将报道如下:1.现场调查该厂建办1983年,产品对氨基苯酚,用于医药中间体,呈米白色结晶。车间厂房不宽敞,无气窗与排风设施,操作反应有气体逸出。年产品720吨/年,生产时间30天/月,24小时分三班作业,8小时/班,实际接触时间3小时/班。2.临床资料1987—1991年五年动态观察体检62名,其中男性40名,女性22名,年均年龄38岁(24～60),平 Since 1987, we have conducted a five-year observation and follow-up on occupational dermatitis of workers who produce nitrophenol in a chemical plant. The reasons for this are related to occupational factors. We will report the following: 1. Investigation on the site In 1983, P-aminophenol, used in pharmaceutical intermediates, was beige crystals. Shop workshop is not spacious, no window and exhaust facilities, the operation of the reaction gas escape. Annual production of 720 tons / year, the production time of 30 days / month, 24 hours in three shifts, 8 hours / shift, the actual contact time 3 hours / shift. 2. clinical data 1987-1991 five-year dynamic observation of 62 physical examinations, of which 40 were males and 22 females, with an average age of 38 years (24 to 60), flat