论文部分内容阅读
目的探讨新生儿窒息后所致缺氧缺血性脑病的脑损伤。方法对于４３例生后１０天内新生儿进行头颅ＭＲＩ检查，其中７例正常新生儿，３６例为缺氧缺血性脑病（ＨＩＥ）。结果根据ＭＲＩ影像特点将ＨＩＥ脑损伤分为：（１）脑实质水肿改变为主：①广泛脑水肿伴基底节区损伤：８／３６；②局灶性脑水肿伴基底节区损伤：１１／３６；③单纯性脑水肿：７／３６。（２）以脑白质改变为主：５／３６。（３）脑实质出血：４／３６，脑室旁梗塞继发出血１／３６，并且对１２例患儿进行随访，其中６例伴基底节区损伤患儿于６个月～１岁时ＭＲＩ仍可见异常Ｔ２低信号或Ｔ２高信号，１例脑室旁梗塞继发出血患儿于８个月时原发病灶呈Ｔ２高信号及Ｔ１低信号病灶信号。结论ＭＲＩ对基底节区微小病灶具有高度敏感性，有助于ＨＩＥ脑损伤的研究并指导治疗及评估预后
Objective To investigate the brain injury caused by neonatal asphyxia after hypoxic-ischemic encephalopathy. Methods Forty-three neonates undergoing MRI were examined in 43 neonates within 10 days after birth, including 7 normal neonates and 36 hypoxic-ischemic encephalopathy (HIE). Results According to the characteristics of MRI images, the brain injury of HIE was divided into: (1) the change of parenchymal edema mainly: ① extensive brain edema with basal ganglia lesions: 8/36; ② focal cerebral edema with basal ganglia lesions: 11 / 36; ③ simple brain edema: 7/36. (2) to change the main white matter: 5/36. (3) Cerebral parenchymal hemorrhage: 4/36, secondary ventricular infarction bleeding 1/36, and 12 cases of children were followed up, of which 6 cases with basal ganglia lesions in children 6 months to 1 year old MRI still Visible abnormal T2 low signal or T2 high signal, a case of cerebral infarction secondary hemorrhage in children at 8 months when the primary lesions were T2 high signal and T1 low signal lesions signal. Conclusion MRI is highly sensitive to the foci of basal ganglia and is helpful for the study of HIE brain injury and for guiding the treatment and evaluating the prognosis