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目的:研究320排CT冠脉造影对分析冠状动脉轻度及重度狭窄患者斑块成分的价值。方法:2011年4月-2012年5月间我院1132例(62±12岁,42%女性)冠心病患者行320排CT冠状动脉造影检查,依据美国心脏协会16分段标准,分析每一例患者每一节段血管狭窄程度及斑块性质,CT斑块分型如下:Ⅰ型为钙化斑块,Ⅱ型为钙化为主的混合斑块,Ⅲ型为非钙化为主的混合斑块,Ⅳ型为非钙化斑块。比较不同狭窄程度组斑块类型差别。结果:共363例为冠脉血管正常人群,冠状动脉狭窄患者共769例,其中管腔狭窄程度<50%的轻度人群为367例,重度狭窄组(≥50%)为402例。重度狭窄患者组冠脉血管混合斑块数量较多,而非钙化斑块相对较少(Ⅰ～Ⅳ型斑块所占比例分别为22%,,39%,21%,18%),轻度狭窄患者组各斑块所占比例分别为29%,29%,26%,16%(p=0.006)。结论:随着冠状动脉狭窄程度的不同,冠状动脉粥样硬化斑块的类型也不尽相同,重度狭窄人群组中混合斑块较多而非钙化斑块较少。320排CT冠脉造影可对冠状动脉斑块成分进行分析。
Objective: To investigate the value of 320-slice CT coronary angiography in the analysis of plaque components in patients with mild and severe coronary artery stenosis. Methods: From April 2011 to May 2012, 1132 CHD patients (62 ± 12 years, 42%) in our hospital underwent 320-slice CT coronary angiography. According to the American Heart Association criteria of 16 segments, each case was analyzed Patients with each segment of vascular stenosis and plaque quality, CT plaque classification is as follows: type Ⅰ calcified plaque, type Ⅱ calcification-based mixed plaque, type Ⅲ non-calcified mixed plaque, Type Ⅳ non-calcified plaque. Compare the different types of plaque group differences in the degree of stenosis. Results: A total of 363 patients with coronary artery stenosis were included in this study. A total of 769 patients with coronary artery stenosis were included, of whom 367 were mild to less than 50%, and 402 were severe stenosis (≥50%). Patients with severe stenosis had a higher number of coronary plaques and fewer noncalcified plaques (22%, 39%, 21% and 18%, respectively), mild The proportion of plaque in the stenosis group was 29%, 29%, 26%, and 16%, respectively (p = 0.006). Conclusion: With the different degree of coronary artery stenosis, the types of coronary atherosclerotic plaque are also different. In severe stenosis group, there are more mixed plaques and less calcified plaque. 320-slice CT coronary angiography can analyze coronary plaque components.